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St. Louis Cardinals at New York Mets Odds, Picks & Prediction

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The New York Mets will win against the St. Louis Cardinals, predicted final score Mets 4, Cardinals 3. Mets edge out with home advantage, better scoring at 4.1 PPG vs Cardinals' 3.8, stronger defense allowing #1 rank in RBI, strikeouts, total bases, hits, and walks to power rankers, plus 3 wins in last 5 H2H.

Quick Facts

Matchup
St. Louis Cardinals at New York Mets
Date
Wednesday, February 25, 2026, 6:10 PM ET
Spread
New York Mets -
Total
O/U TBD
Moneyline
New York Mets - / St. Louis Cardinals -
Best Bet
Mets Spread
Prediction
Mets 4-3

Odds Comparison

Sportsbookawayhomelinemarket
---Spread
--O/U TBDTotal
---Moneyline

Matchup Preview

Both teams enter on identical 4-6 records over their last 10 games and a one-game losing streak. The Mets average 4.1 runs scored per game while allowing 3.9, slightly outperforming the Cardinals' 3.8 PPG scored and 4.7 allowed. Head-to-head in the last 5 meetings: Mets 5 @ Cardinals 6; Mets 0 @ Cardinals 0; Cardinals 4 @ Mets 7; Cardinals 0 @ Mets 3; Cardinals 4 @ Mets 5. Mets hold a 3-1-1 edge in those close contests.

Defensive edges shine: Cardinals allow MLB #1 rank (0/game to PRs) in home runs, RBI, strikeouts, walks, total bases. Mets allow #1 rank (0/game to PRs) in RBI, strikeouts, total bases, walks, hits. Expect low-scoring affair at Citi Field.

By The Numbers

StatMets (Home)Cardinals (Away)
Record (L10)4-64-6
PPG4.13.8
Opp PPG3.94.7
StreakL1L1

Key Injuries

No significant injuries reported for either team.

Odds Analysis

Consensus odds favor the Mets on spread (New York Mets -) and moneyline (New York Mets - / St. Louis Cardinals -), with total O/U TBD. Mets' home form and defensive ranks justify the favoritism despite even L10 records.

Player Props to Watch

Limited prop data available, but focus on Mets hitters vs Cardinals' #1-ranked pitching allowing 0 home runs, RBI, strikeouts, walks, total bases per game to power rankers. Cardinals bats face Mets' elite staff allowing 0 RBI, strikeouts, total bases, walks, hits per game to PRs.

Best Bets

  • Mets Spread (-): Mets' home defense edges and 4.1 PPG scoring overpower Cardinals' 4.7 allowed.
  • Mets Moneyline (-): 3-1-1 H2H record in last 5 supports home win.
  • Under O/U TBD: Both teams' #1 defensive ranks vs PRs suggest low totals like recent H2H (0-0, 0-3).

Prediction

New York Mets 4, St. Louis Cardinals 3. Mets capitalize on defensive dominance and home field in tight battle.

Updated Wednesday, February 25, 2026. All odds and stats powered by SportsClaw — real-time data from 40+ sportsbooks. Get picks on Telegram →

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